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Mithra is the antagonist of Moonlight Syndrome and by extension the Twilight Syndrome games as well, being the cause of the titular syndromes. Although he appears as a young child, Mithra is very violent, manipulative and cruel, killing Yukari Hasegawa, Arisa Kahara, Chisato Itsushima and Mika Kishi. He is killed by Ryo Kazan, who wields a katana to tear him apart in the conclusion of the story, apparently bringing an end to the syndrome.

Mithra also appears in a single scene in killer7 in the Alter Ego chapter, referred to as "The Oracle" in Hand in killer7. His reason for appearing here (apart from giving the killer7 a cryptic message about light and shadow) is unknown, though it may be connected to the full moon appearing at the beginning of each mission. As The Oracle, he appears as twins, one in front of the other, who share the voice of an old man.

In Zoroastrian mythology, Mithra is the god of contract, portrayed as a kind and benevolent figure. This makes his portrayal in Moonlight Syndrome a stark contrast to the original Mithra, appearing in the game as a ruthless villain. Later on, in killer7, he is portrayed in a more neutral manner; instead of forming a contract with the killer7, Mithra simply appears to give them cryptic advice, then disappearing just as suddenly.

killer7 characters
The killer7 Harman Smith ยท Garcian Smith ยท Dan Smith ยท KAEDE Smith ยท Kevin Smith ยท Coyote Smith ยท Con Smith ยท MASK de Smith
The Smith Syndicate Samantha Sitbon ยท Christopher Mills ยท Iwazaru ยท Kikazaru ยท Mizaru ยท Travis Bell ยท Kess BloodySunday ยท Yoon-Hyun ยท Susie Sumner ยท Mad Doctor ยท Gary Wanderers
Heaven Smile Kun Lan ยท Heaven Smile ยท Gatekeeper ยท Kenjiro Matsuoka
Angel Angel ยท Red Gunners ยท Bianca ยท Pussy
Sunset Toru Fukushima ยท Young Guys ร—3 ยท Jean DePaul ยท Julia Kisugi ยท Spencer ยท Hiroyasu Kurahashi ยท Shinya Akiba ยท Hiro Kasai ยท Mary ยท Plenty
Cloudman Andrei Ulmeyda ยท Stacy Spangles ยท Cult Member ยท Old Man ยท Man in Photograph ยท Drug Store Employee ยท Postman ยท Security Guard ยท Gabriel Clemence ยท General Lynch ยท Helga
Encounter Curtis Blackburn ยท Curtis's Bitch ยท AYAME Blackburn ยท Pedro Montana ยท Mary Montana ยท Archangel ยท Xenia
Alter Ego The Handsome Men ยท Steve Thunderson ยท Trevor Pearlharbor ยท Singer ยท Mithra ยท LOVE Wilcox
Smile Linda Vermillion ยท Edo Macalister ยท Dimitri Nightmare ยท Holbert ยท Emir Parkreiner ยท Benjamin Keane ยท Greg Nightmare ยท Solitaire
Lion Last Shot Smile
And... Johnny Gagnon
Hand in killer7 Jaco Checkbox ยท Jim Townsend ยท Susan ยท Graham MacAlister ยท Jack Foley ยท Mr. A
killer is dead Shigeki Birkin ยท Samayoru ยท Mario Castiglioni
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